Isosorbide-5-mononitrate ISMN usually begins acting within 30 minutes and its effects last six to eight hours. Saper RB. If you have ever had an allergic reaction to a medicine. Mayo Clinic; 2021. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. Any use of this site constitutes your agreement to the Terms and Conditions and Privacy Policy linked below. The drug donates nitric oxide to the body, which is similar to all other Isosorbide mononitrates. This information is aggregated and used to produce personalized reports that patients can reference. It will give you more information about nitrate medicines, and it will also provide you with a full list of side-effects which you could experience from taking isosorbide mononitrate. Prescription and OTC Canada residents can call a provincial poison control center. Clipboard, Search History, and several other advanced features are temporarily unavailable. Alcohol, including beer, wine, and spirits, does raise your blood pressure if its consumed in excess. All rights reserved. Synthroid (levothyroxine) Tylenol (acetaminophen) Vitamin B12 (cyanocobalamin) Vitamin C (ascorbic acid) Vitamin D3 (cholecalciferol) Isosorbide mononitrate disease interactions There are 7 disease interactions with isosorbide mononitrate which include: AMI anemia hemodialysis hypotension intracranial pressure hypertrophic cardiomyopathy glaucoma Accessed Sept. 7, 2022. Some conditions may become worse when the drug is suddenly stopped. Although not all of these side effects may occur, if they do occur they may need medical attention.Check with your doctor immediately if any of the following side effects occur:Less commonAbnormal heart soundabsence of or decrease in body movementarm, back, or jaw painblack, tarry stoolsbladder painbleeding after defecationbleeding gumsblood in the urine or stoolsblurred visionbody aches or painburning while urinatingburning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelingschest pain or discomfortchest tightness or heavinesschillscold sweatscoldsconfusionconvulsionscough or hoarsenessdecreased urinediarrheadifficult or labored breathingdifficult, burning, or painful urinationdilated neck veinsdizzinessdizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting positiondry mouthear congestionextra heartbeatsfaintingfast, slow, irregular, pounding, or racing heartbeat or pulsefever or chillsflu-like symptomsfrequent urge to urinatefrequent urinationgeneral feeling of discomfort or illnessheadacheheadache, severe and throbbingheart murmurincreased need to urinateincreased sweatingincreased thirstincreased volume of pale, dilute urineirregular breathingitching, pain, redness, or swelling on the legjoint pain, stiffness, or swellinglightheadednessloss of appetiteloss of voicelower back, side, or stomach painmuscle aches and painsmuscle crampsnasal congestionnausea or vomitingnervousnessnumbness or tingling in the hands, feet, or lipspain or discomfort in the arms, jaw, back, or neckpain, tension, and weakness upon walking that subsides during periods of restpartial or slight paralysispassing urine more oftenpinpoint red or purple spots on the skinpounding in the earsrunny noseshakiness in the legs, arms, hands, or feetshiveringsneezingsore on the legsore throatsudden decrease in the amount of urinesweatingswellingswelling of the face, fingers, feet, or lower legstightness in the chesttrembling or shaking of the hands or feettrouble sleepingtroubled breathinguncomfortable swelling around the anusunusual bleeding or bruisingunusual tiredness or weaknessvomiting of blood or material that looks like coffee groundsweaknessweight gainRareBluish-colored lips, fingernails, or palmsdark urinepale skinrapid heart rateGet emergency help immediately if any of the following symptoms of overdose occur:Symptoms of overdoseBlurred or loss of visionbulging soft spot on the head of an infantchange in consciousnesschange in the ability to see colors, especially blue or yellowcold, clammy skindisturbed color perceptiondouble visionfeeling of constant movement of self or surroundingshalos around lightsheadache, severe and throbbingloss of consciousnessnight blindnessoverbright appearance of lightsparalysissensation of spinningtunnel visionSome side effects may occur that usually do not need medical attention. To provide you with the most relevant and helpful information, and understand which Isosorbide mononitrate Alternatives Compared Isosorbide mononitrate Aspirin Nitroglycerin Prescription only Prescribed for Angina, Heart Failure, Angina Pectoris Prophylaxis. The dose is according to the body weight and severity of the condition. Diabetes treatment: Can cinnamon lower blood sugar? It works more slowly and lasts for about 12 hours, so you only need to take it once a day. It does not work fast enough to relieve the pain of an angina attack that has already started. Drug interactions may change how your medications work or increase your risk for serious side effects. You need to take it every day in order for it to work. coma (loss of consciousness for a period of time). It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. URL of this page: https://medlineplus.gov/druginfo/meds/a682348.html. Epub 2006 Mar 22. Never take more than the prescribed dose. Is isosorbide mononitrate (Monoket) the same as nitroglycerin (Nitrostat)? daily and increasing to 40 mg three times daily as necessary, given at 8 AM, 1 PM, and 6 PM), isosorbide mononitrate (starting at 30 mg/day in the morning and increasing to 120 mg/day as necessary), or a transdermal. What conditions does Isosorbide Mononitrate treat? This form of skin cancer is mostly caused by PhD (Pharmacology) Pursuing, M.Pharma (Pharmacology), B.Pharma - Certificate in Nutrition and Child Care, MBBS, Master in Healthcare Administration, Diploma in Occupational Health, What are the uses of Isosorbide Mononitrate. Any use of this site constitutes your agreement to the Terms and Conditions and Privacy Policy linked below. Accessed Sept. 7, 2022. Browse Drugs and Medicines. Other medications may be prescribed by your doctor for these conditions. Coenzyme Q-10 Natural Medicines. 1998 Oct;61(10):577-83. If you miss a dose, take it as soon as you remember. Your body can get used to isosorbide mononitrate (Monoket), and the same amount of medication might no longer work as well as it used to. This document does not contain all possible drug interactions. Your dose may need to be gradually decreased. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API). Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them: continuing ringing or buzzing or other unexplained noise in the ears, dull ache or feeling of pressure or heaviness in the legs, excess air or gas in the stomach or intestines, increased sensitivity of the eyes to sunlight, loss in sexual ability, desire, drive, or performance, pain or tenderness around the eyes and cheekbones, redness of the face, neck, arms, and occasionally, upper chest, redness, pain, swelling of the eye, eyelid, or inner lining of the eyelid, redness, swelling, or soreness of the tongue, small clicking, bubbling, or rattling sounds in the lung when listening with a stethoscope, stomach bloating, burning, cramping, or pain, terrifying dreams causing sleep disturbances, uncontrolled twisting movements of the neck, white patches in the mouth, tongue, or throat. Nitrates, although important for the management of angina pectoris, cause significant headache in many patients. Headache and weakness of left side (both arm and leg) may suggest a brain pathology. What are the side effects of Isosorbide Mononitrate ? FOIA The authors assessed the occurrence of angina pectoris and headache by diary cards while taking into account the number of isosorbide dinitrate sublingual puffs and paracetamole tablets required. 1994 Jan;15(1):108-13. doi: 10.1093/oxfordjournals.eurheartj.a060361. The information eHealthMe analyzes includes: Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. This product may contain inactive ingredients, which can cause allergic reactions or other problems. What special dietary instructions should I follow? Higher dosages are associated with stomach irritation and When used regularly on a long-term basis, this helps prevent angina attacks from occurring. Your doctor may decide not to treat you with this medication or change some of the other medicines you take. Journals of the American College of Cardiology. National Library of Medicine 67% of reviewers reported a positive effect, while 13% reported a negative effect. 2023 eHealthMe.com. That's why you need to talk with your health care provider before you take herbal supplements if you take prescription medicines. ask your doctor about the safe use of alcoholic beverages while you are taking isosorbide. Registered in England and Wales. Take this medication by mouth as directed by your doctor, usually twice a day. Although unlikely, when this medication is used for a long time, it may not work as well and may require different dosing. Healthcare data is obtained from a number of sources including the Food and Drug Administration (FDA). It will not treat an angina attack that has already begun. Natural Medicines. Modified-release nitrate preparations: use a once-daily dose to maintain a nitrate-low period and thus minimize tolerance. Additionally, TRUVEN HEALTH MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON REUTERS HEALTHCARE PRODUCTS. Isosorbide mononitrate (Monoket) is available as both a immediate-release (IR, short-acting) and extended-release (ER, long-acting) tablet. Your doctor may recommend treating headaches with an over-the-counter pain reliever (such as acetaminophen, aspirin). The narrowing makes it more difficult for blood to flow to your heart muscle. Higher than recommend dosage of sublingual isosorbide dinitrate for treating angina pectoris: a case report and review of the literature. This medication belongs to a class of drugs known as nitrates. Accessed Sept. 7, 2022. Evening primrose. Your provider might temporarily have you stop isosorbide mononitrate (Monoket) if this happens. 8.0 out of 10 from a total of The IR version can help treat and prevent angina. Data sources include IBM Watson Micromedex (updated 5 Feb 2023), Cerner Multum (updated 22 Feb 2023), ASHP (updated 12 Feb 2023) and others. Advertising revenue supports our not-for-profit mission. Isosorbide mononitrate (Monoket) is good for a specific type of chest pain (called angina), but it can cause headaches or dizziness after you take it. Isosorbide mononitrate (Monoket) is a nitrate vasodilator. Data were assessed for carryover and time effects. Accessed Sept. 7, 2022. The information on this page is written and peer reviewed by qualified clinicians. The information contained in the Truven Health Micromedex products as delivered by GoodRx is intended as an educational aid only. It relaxes blood vessels in your body (causing them to widen) and this reduces the strain on your heart, making it easier for your heart to pump blood around your body. All rights reserved. Medicines containing Isosorbide Mononitrate. and transmitted securely. With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. Some products have ingredients that could worsen your heart failure. Isosorbide mononitrate (Monoket) is available as a generic medication and may be significantly cheaper compared to the brand version. If you have an underactive thyroid gland. Otherwise, call a poison control center right away. This activity describes the indications, action, and contraindications for isosorbide as a valuable agent in treating angina pectoris due to coronary artery disease, heart failure with reduced . Mayo Clinic on Incontinence - Mayo Clinic Press, NEW The Essential Diabetes Book - Mayo Clinic Press, NEW Ending the Opioid Crisis - Mayo Clinic Press, FREE Mayo Clinic Diet Assessment - Mayo Clinic Press, Mayo Clinic Health Letter - FREE book - Mayo Clinic Press. Select a condition to view a list of medication options. You may report side effects to Health Canada at 1-866-234-2345. Yes, it's good for health but don't take it excesse in amount, use once daily for 1 month then stop it or take once a weekly. Conclusions: Store in a cool, dry place, away from direct heat and light. In the US - Call your doctor for medical advice about side effects. In Canada - Call your doctor for medical advice about side effects. Trapidil is as effective as isosorbide-dinitrate for treating stable angina pectoris: a multinational, multicenter, double-blind, randomized study. if you are having surgery, including dental surgery, tell the doctor or dentist that you are taking isosorbide. This content does not have an English version. 55 ratings on Drugs.com. Isosorbide mononitrate should not be used in patients with severe anaemia, severe hypotension, closed angle glaucoma or severe hypovolaemia.Isosorbide mononitrate may give rise to postural hypotension and syncope in some patients. It is not suitable to take to treat an angina attack - you should always carry with you a short-acting nitrate, such as glyceryl trinitrate (GTN), for if you get angina pain. Mehta D. Herbal & dietary supplements. Although not all of these side effects may occur, if they do occur they may need medical attention. It works by relaxing the blood vessels and increasing the supply of blood and oxygen to the heart while reducing its workload. Isosorbide mononitrate helps to prevent angina chest pain from developing. tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. Isosorbide mononitrate is used to prevent angina (chest pain) caused by coronary artery disease (heart disease). Erectile dysfunction medications (e.g., sildenafil (Viagra), vardenafil (Levitra), tadalafil (Cialis)) cannot be taken while you're taking isosorbide mononitrate (Monoket). you should know that isosorbide may cause dizziness, lightheadedness, and fainting when you get up too quickly from a lying position, or at any time, especially if you have been drinking alcoholic beverages. Highly clinically significant. If you forget to take a dose, take it as soon as you remember. This site complies with the HONcode standard for trustworthy health information: verify here. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Liperoti R, et al. B12 and folic acid is essential along with iron. The most common side-effect is headache. McGraw Hill; 2022. https://accessmedicine.mhmedical.com/search.
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